Sansulin Log-G Dispopen

Insulin glargine

DM in adult, adolescent & childn ≥2 yr.

SC Individualized dosage.

Hypersensitivity.

Not for IV administration. Not the insulin of choice for the treatment of diabetic ketoacidosis. Hyper- or hypoglycaemic episodes. Patients w/ significant stenoses of the coronary arteries or blood vessels supplying the brain; proliferative retinopathy not treated w/ photoco­agulation; autonomic neuropathy; long history of diabetes; psychiatric illness. Intensify blood glucose monitoring. Increased susceptibility to hypoglycaemia in case of change in inj area; improved insulin sensitivity; unaccustomed, increased or prolonged physical activity; intercurrent illness; inadequate food intake; missed meals; alcohol consumption; certain uncompensated endocrine disorders; concomitant treatment w/ certain other medicinal products. Hyperglycemia may occur in case of omission or reduction of inj or decreased insulin effectiveness; decreased physical activity, stress situations, injuries, operations, feverish illness or other certain disease. May impair ability to drive or use machines. Insulin requirement may be diminished in patients w/ renal impairment or severe hepatic impairment. Pregnancy & lactation. Childn <6 yr. Elderly.

Hypoglycemia; temporary visual impairment; lipodystrophy, inj site & allergic reactions (eg, redness, pain, itching, hives, swelling or inflammation).

Oral antidiabetic agents, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, pentoxifylline, propoxyphene, salicylates & sulfonamide antibiotics may enhance the blood-glucose-lowering effect & increase susceptibility to hypoglycemia. Corticosteroids, danazol, diazoxide, diuretics, glucagon, INH, estrogens & progestogens, phenothiazine derivatives, somatropin, sympathomimetic agents (eg, epinephrine (adrenaline), salbutamol, terbutaline), & thyroid hormones may reduce blood glucose-lowering effect. β-blockers, clonidine, lithium salts or alcohol may either potentiate or weaken blood-glucose-lowering effect. Pentamidine may cause hypoglycemia, which may be followed by hyperglycemia. Signs of adrenergic counter-regulation may be reduced or absent w/ sympathomimetics eg, β-blockers, clonidine, guanethidine & reserpin.

Insulin Preparations

A10AE04 - insulin glargine ; Belongs to the class of long-acting insulins and analogues for injection. Used in the treatment of diabetes.

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